Identification of Epigenetic Aberrant Promoter Methylation in Serum DNA Is Useful for Early Detection of Lung Cancer

2005202 citationsJournal Articlebronze Open Access

Authors

Keiichi Fujiwara · Okayama University

Nobukazu Fujimoto · Okayama University

Masahiro Tabata · Okayama University

Kenji Nishii · Okayama Prefecture

Keitaro Matsuo · Aichi Cancer Center

Katsuyuki Hotta · Okayama University

Toshiyuki Kozuki ·

Abstract

These results suggest that identification of promoter methylation of tumor suppressor genes in serum DNA could be useful for early detection of lung cancer.

Topics & Keywords

Epigenetics and DNA Methylation RNA modifications and cancer Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 11, Issue 3, pp. 1219-1225

DOI: 10.1158/1078-0432.1219.11.3

Field-Weighted Citation Impact: 5.17