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Insulin Needs after CD3-Antibody Therapy in New-Onset Type 1 Diabetes

20051,087 citationsJournal Articlebronze Open Access

Authors

Bart Keymeulen · Center for Beta Cell Therapy in Diabetes

Evy Vandemeulebroucke · Center for Beta Cell Therapy in Diabetes

Anette G. Ziegler · München Klinik Schwabing

Chantal Mathieu · KU Leuven

Leonard Kaufman

G Hale · Sir Robert McAlpine (United Kingdom)

Frans Gorus · Center for Beta Cell Therapy in Diabetes

Abstract

Short-term treatment with CD3 antibody preserves residual beta-cell function for at least 18 months in patients with recent-onset type 1 diabetes.

Topics & Keywords

Diabetes and associated disorders Diabetes Management and Research Pancreatic function and diabetes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 352, Issue 25, pp. 2598-2608

DOI: 10.1056/nejmoa043980

Field-Weighted Citation Impact: 43.59

Insulin Needs after CD3-Antibody Therapy in New-Onset Type 1 Diabetes | Researchclopedia

Michel Goldman · Université Libre de Bruxelles

Markus Walter · München Klinik Schwabing

Sophie Candon · Inserm

Liliane Schandené · Université Libre de Bruxelles

Laurent Crenier · Erasmus Hospital

Christophe De Block · Antwerp University Hospital

Jean‐Marie Seigneurin · Centre Hospitalier Universitaire de Grenoble

Pieter De Pauw · Diabetes Research Center

Denis Piérard · Center for Beta Cell Therapy in Diabetes

Ilse Weets · Diabetes Research Center

Peppy Rebello · Sir Robert McAlpine (United Kingdom)

Pru Bird · Sir Robert McAlpine (United Kingdom)

Eleanor Berrie · Sir Robert McAlpine (United Kingdom)

Mark R. Frewin · Sir Robert McAlpine (United Kingdom)

Herman Waldmann · Sir Robert McAlpine (United Kingdom)

Jean‐François Bach · Hôpital Necker-Enfants Malades

Daniël Pipeleers · Diabetes Research Center

Lucienne Chatenoud · Inserm