Population pharmacokinetics of artesunate and amodiaquine in African children

200979 citationsJournal Articlegold Open Access

Authors

Kasia Stepniewska · Mahidol Oxford Tropical Medicine Research Unit

Walter Taylor · Hôpital Beau-Séjour

Sodiomon B. Sirima · Centre National de Recherche et de Formation sur le Paludisme

Esperance B Ouedraogo · Centre National de Recherche et de Formation sur le Paludisme

Alphonse Ouédraogo · Centre National de Recherche et de Formation sur le Paludisme

Adama Gansané · Centre National de Recherche et de Formation sur le Paludisme

Abstract

The bioavailability of the co-formulated AS-AQ FDC was similar to that of the separate tablets for desethylamodiaquine, DHA and the total anti-malarial activity. These data support the use this new AS-AQ FDC in children with acute uncomplicated falciparum malaria.

Topics & Keywords

Malaria Research and Control Drug-Induced Hepatotoxicity and Protection Computational Drug Discovery Methods

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Malaria Journal

Volume 8, Issue 1, pp. 200-200

DOI: 10.1186/1475-2875-8-200

Field-Weighted Citation Impact: 6.87