Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction

20034,883 citationsJournal Articlebronze Open Access

Authors

Bertram Pitt · University of Michigan–Ann Arbor

Willem J. Remme

Faı̈ez Zannad · Centre d’Investigation Clinique Innovation Technologique de Nancy

James D. Neaton · University of Minnesota System

Felipe A. Martínez · Instituto Médico DAMIC

Abstract

The addition of eplerenone to optimal medical therapy reduces morbidity and mortality among patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure.

Topics & Keywords

Hormonal Regulation and Hypertension Heart Failure Treatment and Management Blood Pressure and Hypertension Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 348, Issue 14, pp. 1309-1321

DOI: 10.1056/nejmoa030207

Field-Weighted Citation Impact: 160.28