Transcriptional Response to Hypoxia in Human Tumors

2001326 citationsJournal Articlebronze Open Access

Authors

Anita Lal · Duke University Hospital

Hans Peters

Gregory J. Riggins · Duke Medical Center

Abstract

We have identified the genes that are transcriptionally activated within hypoxic malignant cells, a crucial first step in understanding the complex interactions driving hypoxia response. Within our catalogue of hypoxia-responsive genes are novel candidates for hypoxia-driven angiogenesis.

Topics & Keywords

Cancer, Hypoxia, and Metabolism Angiogenesis and VEGF in Cancer Cancer, Lipids, and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 93, Issue 17, pp. 1337-1343

DOI: 10.1093/jnci/93.17.1337

Field-Weighted Citation Impact: 9.57