Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection

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Authors

Lewis H. Kuller · University of Pittsburgh

Russell P. Tracy · University of Vermont

Waldo Belloso · Hospital Italiano de Buenos Aires

Stéphane De Wit · Centre Hospitalier Universitaire de Saint-Pierre

Fraser Drummond · National Centre for Clinical Research on Emerging Drugs

H. Clifford Lane · National Institute of Allergy and Infectious Diseases

Bruno Ledergerber

Abstract

IL-6 and D-dimer were strongly related to all-cause mortality. Interrupting ART may further increase the risk of death by raising IL-6 and D-dimer levels. Therapies that reduce the inflammatory response to HIV and decrease IL-6 and D-dimer levels may warrant investigation.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS Medicine

Volume 5, Issue 10, pp. e203-e203

DOI: 10.1371/journal.pmed.0050203

Field-Weighted Citation Impact: 70.53