Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

20081,289 citationsJournal Article

Authors

Christophe Piot · Hôpital Arnaud de Villeneuve

Pierre Croisille · Université Claude Bernard Lyon 1

Patrick Staat · Université Claude Bernard Lyon 1

Hélène Thibault · Inserm

Gilles Rioufol · Hospices Civils de Lyon

Nathan Mewton · Hospices Civils de Lyon

Rachid Elbelghiti ·

Abstract

In our small, pilot trial, administration of cyclosporine at the time of reperfusion was associated with a smaller infarct by some measures than that seen with placebo. These data are preliminary and require confirmation in a larger clinical trial.

Topics & Keywords

Cardiac Ischemia and Reperfusion Cardiac Imaging and Diagnostics Cardiac Arrest and Resuscitation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 359, Issue 5, pp. 473-481

DOI: 10.1056/nejmoa071142

Field-Weighted Citation Impact: 64.69