Comparative analysis of gingival tissue antigen presentation pathways in ageing and periodontitis

201348 citationsJournal Article

Authors

Octavio A. González · Lexington VA Health Care System

M. John Novak · University of Kentucky

Sreenatha Kirakodu · University of Kentucky

Luis Orraca · University of Puerto Rico System

Kuey‐Chu Chen · University of Kentucky

Arny J. Stromberg · University of Kentucky

Janis González‐Martínez

Abstract

These transcriptional changes suggest a response of healthy ageing tissues through the class II pathway (i.e. endocytosed antigens) and altered responses in periodontitis that could reflect host-associated self-antigens or targeting cytosolic intracellular microbial pathogens.

Topics & Keywords

Immunotherapy and Immune Responses Immune Response and Inflammation T-cell and B-cell Immunology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal Of Clinical Periodontology

Volume 41, Issue 4, pp. 327-339

DOI: 10.1111/jcpe.12212

Field-Weighted Citation Impact: 1.32