Therapeutic Potential of Nrf2 Activators in Streptozotocin-Induced Diabetic Nephropathy

2011499 citationsJournal Articlebronze Open Access

Authors

Hongting Zheng · Army Medical University

Samantha A. Whitman · University of Arizona

Wei Wu · Xinqiao Hospital

Georg T. Wondrak · University of Arizona

Pak Kin Wong · University of Arizona

Deyu Fang · Northwestern University

Donna D. Zhang ·

Abstract

We provide experimental evidence indicating that dietary compounds targeting Nrf2 activation can be used therapeutically to improve metabolic disorder and relieve renal damage induced by diabetes.

Topics & Keywords

Genomics, phytochemicals, and oxidative stress Biochemical Acid Research Studies Chemotherapy-induced organ toxicity mitigation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Diabetes

Volume 60, Issue 11, pp. 3055-3066

DOI: 10.2337/db11-0807

Field-Weighted Citation Impact: 11.29