Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy

20051,881 citationsJournal Articlebronze Open Access

Authors

Roman Rouzier · Institut Gustave Roussy

Charles M. Perou · UNC Lineberger Comprehensive Cancer Center

W. Fraser Symmans

Nuhad K. Ibrahim

Massimo Cristofanilli

K. Anderson · Applied Mathematics (United States)

Kenneth R. Hess · Applied Mathematics (United States)

James Stec · Albany Medical Center Hospital

Abstract

The basal-like and erbB2+ subtypes of breast cancer are more sensitive to paclitaxel- and doxorubicin-containing preoperative chemotherapy than the luminal and normal-like cancers.

Topics & Keywords

Breast Cancer Treatment Studies HER2/EGFR in Cancer Research Gene expression and cancer classification

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 11, Issue 16, pp. 5678-5685

DOI: 10.1158/1078-0432.ccr-04-2421

Field-Weighted Citation Impact: 37.36