Active specific immunotherapy with a beta-human chorionic gonadotropin peptide vaccine in patients with metastatic colorectal cancer: antibody response is associated with improved survival.

2002146 citationsJournal Article

Authors

Hong M. Moulton · Sarepta Therapeutics (United States)

Abstract

Vaccination with CTP37-DT induced anti-hCG antibodies in most patients with advanced colorectal cancer. Anti-hCG antibody induction was associated with longer overall survival. CTP37-DT has an excellent safety profile and warrants further study in patients with colorectal cancer.

Topics & Keywords

Glycosylation and Glycoproteins Research Immunotherapy and Immune Responses Toxin Mechanisms and Immunotoxins

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PubMed

Volume 8, Issue 7, pp. 2044-51

Field-Weighted Citation Impact: 2.45