A Longitudinal Study of Plasma and Urinary Cortisol in Pregnancy and Postpartum

2011381 citationsJournal Articlebronze Open Access

Authors

Caroline Jung · St Vincent's Hospital

Jui T. Ho

David J. Torpy · University of Adelaide

Anne Rogers · Flinders University

Matthew Doogue · Flinders Medical Centre

John G. Lewis · Canterbury Health Laboratories

Raymond Czajko · The Royal Melbourne Hospital

Abstract

Our study demonstrated elevations in total plasma cortisol and CBG concentrations during pregnancy and with low-dose OCP use. Pregnancy was also associated with significant increases in plasma free cortisol and UFC, suggesting that the rise in total plasma cortisol is contributed to by up-regulation of the maternal hypothalamic-pituitary-adrenal axis in addition to elevated CBG.

Topics & Keywords

Hormonal Regulation and Hypertension Electrolyte and hormonal disorders Maternal Mental Health During Pregnancy and Postpartum

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 96, Issue 5, pp. 1533-1540

DOI: 10.1210/jc.2010-2395

Field-Weighted Citation Impact: 8.40