Hallmarks of epithelial to mesenchymal transition are detectable in Crohn's disease associated intestinal fibrosis

2015115 citationsJournal Articlegold Open Access

Authors

Michael Scharl · University Hospital of Zurich

N. King Huber · University Hospital of Zurich

Silvia Lang · University Hospital of Zurich

Alois Fürst · Caritas-Krankenhaus St. Josef

E. C. Jehle · Ravensburg University of Cooperative Education

Gerhard Rogler · Swiss Integrative Center for Human Health

Abstract

We demonstrate the presence of EMT-associated molecules in fibrotic lesions of CD patients. These findings support the hypothesis that EMT might play a role for the development of CD-associated intestinal fibrosis.

Topics & Keywords

Inflammatory Bowel Disease Helicobacter pylori-related gastroenterology studies Digestive system and related health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical and Translational Medicine

Volume 4, Issue 1, pp. 1-1

DOI: 10.1186/s40169-015-0046-5

Field-Weighted Citation Impact: 8.89