Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India

2008177 citationsJournal Articlegold Open Access

Authors

Vidhan Jain · National Institute of Malaria Research

Henry B Armah · Morehouse School of Medicine

Jon Eric Tongren · Centers for Disease Control and Prevention

Renée M. Ned · National Center for Infectious Diseases

Nana O. Wilson · Morehouse School of Medicine

Sara Crawford · Division of Parasitic Diseases and Malaria

Pradeep K. Joel

Abstract

The results suggest that plasma levels of IP-10, sTNF-R2 and sFas may be potential biomarkers of CM severity and mortality. VEGF was found to be protective against CM associated mortality and may be considered for adjunctive therapy to improve the treatment outcome in CM patients.

Topics & Keywords

Malaria Research and Control Mosquito-borne diseases and control Phagocytosis and Immune Regulation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Malaria Journal

Volume 7, Issue 1, pp. 83-83

DOI: 10.1186/1475-2875-7-83

Field-Weighted Citation Impact: 14.89