Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes

200712 citationsJournal Articlegold Open Access

Authors

Kuo Ping Chiu · Genome Institute of Singapore

Pramila Ariyaratne · Genome Institute of Singapore

Xu Han · Genome Institute of Singapore

Adrian Tan · Genome Institute of Singapore

Patrick Ng · Genome Institute of Singapore

Edison Tak‐Bun Liu · Genome Institute of Singapore

Yijun Ruan ·

Abstract

The highly correlated results unmistakably point to a systematic downregulation of mitochondrial activities, which we hypothesize aims to downgrade the mitochondria-mediated apoptosis and the dependency of cancer cells on angiogenesis. Our results also demonstrate the advantage of using the PET approach in conjunction with KEGG database for systematic pathway analysis.

Topics & Keywords

Genomics and Chromatin Dynamics Epigenetics and DNA Methylation Molecular Biology Techniques and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Cancer

Volume 7, Issue 1, pp. 109-109

DOI: 10.1186/1471-2407-7-109

Field-Weighted Citation Impact: 0.67