Enhanced Expression of Janus Kinase–Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

2008315 citationsJournal Articlehybrid Open Access

Authors

Céline C. Berthier · University of Michigan–Ann Arbor

Hongyu Zhang · University of Michigan–Ann Arbor

MaryLee Schin · University of Michigan–Ann Arbor

Anna Henger · University of Michigan–Ann Arbor

Robert G. Nelson · National Institute of Diabetes and Digestive and Kidney Diseases

Berne Yee · Southwest Kidney Institute

Anissa Boucherot

Abstract

These data suggest a direct relationship between tubulointerstitial Jak/Stat expression and progression of kidney failure in patients with type 2 diabetic nephropathy and distinguish progressive human diabetic nephropathy from nonprogressive murine diabetic nephropathy.

Topics & Keywords

Chronic Kidney Disease and Diabetes Renal Diseases and Glomerulopathies Phytochemical and Pharmacological Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Diabetes

Volume 58, Issue 2, pp. 469-477

DOI: 10.2337/db08-1328

Field-Weighted Citation Impact: 6.46