Prevention of Coronary Heart Disease with Pravastatin in Men with Hypercholesterolemia

19957,469 citationsJournal Articlebronze Open Access

Authors

James Shepherd · Glasgow Royal Infirmary

Stuart M. Cobbe · University of Glasgow

Ian Ford · University of Glasgow

Christopher Isles

A R Lorimer · University of Glasgow

Peter W. Macfarlane · Glasgow Royal Infirmary

James H. McKillop · Glasgow Royal Infirmary

Abstract

Treatment with pravastatin significantly reduced the incidence of myocardial infarction and death from cardiovascular causes without adversely affecting the risk of death from noncardiovascular causes in men with moderate hypercholesterolemia and no history of myocardial infarction.

Topics & Keywords

Lipoproteins and Cardiovascular Health Statistical Methods in Clinical Trials Hormonal and reproductive studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 333, Issue 20, pp. 1301-1308

DOI: 10.1056/nejm199511163332001

Field-Weighted Citation Impact: 346.02