Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach

20052,251 citationsJournal Articlebronze Open Access

Authors

Chaysavanh Manichanh · Virologie et Immunologie Moléculaires

L Rigottier-Gois · Virologie et Immunologie Moléculaires

E Bonnaud · Virologie et Immunologie Moléculaires

K Gloux · Virologie et Immunologie Moléculaires

E Pelletier · Genoscope

L Frangeul · Institut Pasteur

R Nalin

C Jarrin

P Chardon

Abstract

The metagenomic approach allowed us to detect a reduced complexity of the bacterial phylum Firmicutes as a signature of the faecal microbiota in patients with CD. It also indicated the presence of new bacterial species.

Topics & Keywords

Gut microbiota and health Inflammatory Bowel Disease Mycobacterium research and diagnosis

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Gut

Volume 55, Issue 2, pp. 205-211

DOI: 10.1136/gut.2005.073817

Field-Weighted Citation Impact: 16.84