Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells

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Authors

Yong Zhang · Second Affiliated Hospital of Xi'an Jiaotong University

Rongliang Xue · Second Affiliated Hospital of Xi'an Jiaotong University

Zhenni Zhang · Second Affiliated Hospital of Xi'an Jiaotong University

Xia Yang · Second Affiliated Hospital of Xi'an Jiaotong University

Hongyang Shi · Second Affiliated Hospital of Xi'an Jiaotong University

Abstract

The results suggest that linoleic acid promotes cell apoptosis through the release of cytochrome C, only if the intracellular calcium flux is unperturbed and intact. These results confirm that ER stress contributes to fatty acid-induced liver cell apoptosis.

Topics & Keywords

Endoplasmic Reticulum Stress and Disease Liver Disease Diagnosis and Treatment Autophagy in Disease and Therapy

Publication Details

Published in: Lipids in Health and Disease

Volume 11, Issue 1, pp. 1-1

DOI: 10.1186/1476-511x-11-1

Field-Weighted Citation Impact: 12.08

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Palmitic and linoleic acids induce ER stress and apoptosis in hepatoma cells

Authors

Abstract

Topics & Keywords

Publication Details