A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk

201384 citationsJournal Article

Authors

Meian He · Guangxi Medical University

Chen Wu · Chinese Academy of Medical Sciences & Peking Union Medical College

Jianfeng Xu · Huashan Hospital

Huan Guo · Huazhong University of Science and Technology

Handong Yang · Dongfeng Motor (China)

Xiaomin Zhang · Huazhong University of Science and Technology

Jielin Sun

Abstract

This study identified several loci associated with CA19-9, CEA and AFP concentrations. The ABO variants were associated with risk of OSCC and pancreatic cancers and AFP variants with risk of hepatocellular cancer.

Topics & Keywords

Pancreatic and Hepatic Oncology Research Epigenetics and DNA Methylation Neuroendocrine Tumor Research Advances

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gut

Volume 63, Issue 1, pp. 143-151

DOI: 10.1136/gutjnl-2012-303434

Field-Weighted Citation Impact: 3.08