In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer

2009945 citationsJournal Articlebronze Open Access

Authors

Franck Pagès · Fondation ARC pour la Recherche sur le Cancer

Amos Kirilovsky · Ministry of Science

Bernhard Mlecnik · Fondation ARC pour la Recherche sur le Cancer

Martin Asslaber · Medical University of Graz

Marie Tosolini · Austrian Academy of Sciences

Gabriela Bindea · Inserm

Christine Lagorce

Abstract

The combined analysis of CD8(+) plus CD45RO(+) cells in specific tumor regions could provide a useful criterion for the prediction of tumor recurrence and survival in patients with early-stage colorectal cancer.

Topics & Keywords

Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses Colorectal Cancer Treatments and Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 27, Issue 35, pp. 5944-5951

DOI: 10.1200/jco.2008.19.6147

Field-Weighted Citation Impact: 14.32