Detection of Vitamin B12 Deficiency in Older People by Measuring Vitamin B12 or the Active Fraction of Vitamin B12, Holotranscobalamin

2007137 citationsJournal Articlebronze Open Access

Authors

Robert Clarke · University of Oxford

Paul Sherliker · University of Oxford

Harold Hin · Highbury Hospital

Ebba Nexø · Aarhus University Hospital

Anne Mette Hvas · Aarhus University Hospital

Joern Schneede · Umeå University

Jacqueline Birks ·

Abstract

HoloTC has a modestly superior diagnostic accuracy compared with conventional vitamin B(12) for the detection of vitamin B(12) deficiency, but neither test can be recommended to screen asymptomatic populations.

Topics & Keywords

Folate and B Vitamins Research Nutrition and Health in Aging Diet and metabolism studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Chemistry

Volume 53, Issue 5, pp. 963-970

DOI: 10.1373/clinchem.2006.080382

Field-Weighted Citation Impact: 10.34