Extracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem Cells

2012453 citationsJournal Articlebronze Open Access

Authors

Jianhua Zhang · University of Michigan–Ann Arbor

Matthew Klos · University of California, Santa Barbara

Gisela F. Wilson · University of Wisconsin–Madison

Amanda M. Herman · Cellular Dynamics International (United States)

Xiaojun Lian · University of Michigan–Ann Arbor

Kunil Raval · University of Michigan–Ann Arbor

Matthew Barron

Abstract

Dynamic extracellular matrix application promoted epithelial-mesenchymal transition of human PSCs and complemented growth factor signaling to enable robust cardiac differentiation.

Topics & Keywords

Tissue Engineering and Regenerative Medicine Pluripotent Stem Cells Research Mesenchymal stem cell research

Publication Details

Published in: Circulation Research

Volume 111, Issue 9, pp. 1125-1136

DOI: 10.1161/circresaha.112.273144

Field-Weighted Citation Impact: 45.25

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Extracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem Cells

Authors

Abstract

Topics & Keywords

Publication Details