Glial and neuronal markers in cerebrospinal fluid predict progression in multiple sclerosis

2015163 citationsJournal Articlehybrid Open Access

Authors

M. Alba Mañé-Martínez · Universidad Rovira i Virgili

Bob Olsson · University of Gothenburg

Laura Bau · Universitat de Barcelona

Elisabet Matas · Bellvitge University Hospital

Álvaro Cobo Calvo · Universitat de Barcelona

Ulf Andréasson · University of Gothenburg

Kaj Blennow ·

Abstract

CSF levels of NFL in CIS patients are an independent prognostic marker for conversion to CDMS. Whereas, CSF levels of YKL-40 and GFAP are independent prognostic markers for disability progression in MS.

Topics & Keywords

Multiple Sclerosis Research Studies Neuroinflammation and Neurodegeneration Mechanisms Autoimmune and Inflammatory Disorders Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Multiple Sclerosis Journal

Volume 21, Issue 5, pp. 550-561

DOI: 10.1177/1352458514549397

Field-Weighted Citation Impact: 9.75