A Randomized, Controlled Trial of an Aerosolized Vaccine against Measles

201590 citationsJournal Articlebronze Open Access

Authors

Nicola Low · University of Bern

Ashish Bavdekar · King Edward Memorial Hospital Research Centre

Lakshmanan Jeyaseelan · Christian Medical College & Hospital

Siddhivinayak Hirve · Baba Memorial Hospital

Kavitha Ramanathan · Christian Medical College & Hospital

Nicholas J. Andrews

Naseem Shaikh · ICMR-National Institute of Virology

Abstract

Aerosolized vaccine against measles was immunogenic, but, at the prespecified margin, the aerosolized vaccine was inferior to the subcutaneous vaccine with respect to the rate of seropositivity. (Funded by the Bill and Melinda Gates Foundation; Measles Aerosol Vaccine Project Clinical Trials Registry-India number, CTRI/2009/091/000673.).

Topics & Keywords

Virology and Viral Diseases Vaccine Coverage and Hesitancy COVID-19 epidemiological studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 372, Issue 16, pp. 1519-1529

DOI: 10.1056/nejmoa1407417

Field-Weighted Citation Impact: 7.20