Chorionic plate arterial function is altered in maternal obesity

201334 citationsJournal Articlehybrid Open Access

Authors

Christina Hayward · Manchester Academic Health Science Centre

Lucy Higgins · University of Manchester

Elizabeth Cowley · St Mary's Hospital

Susan Greenwood · Manchester Academic Health Science Centre

Tracey Mills · University of Manchester

C.P. Sibley · St Mary's Hospital

Mark Wareing

Abstract

Maternal obesity is associated with altered placental vascular function which may adversely affect placental oxygen and nutrient transport, placing the fetus at risk. Leptin incubation altered CPA vascular function but did not reproduce the obese phenotype.

Topics & Keywords

Pregnancy and preeclampsia studies Gestational Diabetes Research and Management Birth, Development, and Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Placenta

Volume 34, Issue 3, pp. 281-287

DOI: 10.1016/j.placenta.2013.01.001

Field-Weighted Citation Impact: 5.37