Placebo-Controlled Trial of Amantadine for Severe Traumatic Brain Injury

2012787 citationsJournal Articlebronze Open Access

Authors

Joseph T. Giacino · Harvard University

John Whyte · Moss Rehabilitation Hospital

Emilia Bagiella · Columbia University

David Long · Bryn Mawr Rehabilitation Hospital

Douglas I. Katz

Abstract

Amantadine accelerated the pace of functional recovery during active treatment in patients with post-traumatic disorders of consciousness. (Funded by the National Institute on Disability and Rehabilitation Research; ClinicalTrials.gov number, NCT00970944.).

Topics & Keywords

Traumatic Brain Injury Research Traumatic Brain Injury and Neurovascular Disturbances Cardiac Arrest and Resuscitation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 366, Issue 9, pp. 819-826

DOI: 10.1056/nejmoa1102609

Field-Weighted Citation Impact: 37.59