Therapeutic Targeting of Integrin αvβ6 in Breast Cancer

2014139 citationsJournal Articlehybrid Open Access

Authors

Kate M. Moore · Biogen (United States)

Gareth J. Thomas · Queen Mary University of London

Stephen W. Duffy · Nottingham City Hospital

Jane Warwick · Cancer Research UK

Rhian Gabe · Biogen (United States)

Patrick Chou · Southampton General Hospital

Ian O. Ellis ·

Abstract

Targeting αvβ6 with 264RAD alone or in combination with trastuzumab may provide a novel therapy for treating high-risk and trastuzumab-resistant breast cancer patients.

Topics & Keywords

Cell Adhesion Molecules Research HER2/EGFR in Cancer Research Caveolin-1 and cellular processes

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 106, Issue 8

DOI: 10.1093/jnci/dju169

Field-Weighted Citation Impact: 5.72

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Therapeutic Targeting of Integrin αvβ6 in Breast Cancer

Authors

Abstract

Topics & Keywords

Publication Details