A Multi-center, Dose-escalation Study of Human type I Pancreatic Elastase (PRT-201) Administered after Arteriovenous Fistula Creation

201255 citationsJournal Articlehybrid Open Access

Authors

Eric K. Peden · Methodist Hospital

David B. Leeser · NewYork–Presbyterian Hospital

Bradley S. Dixon · University of Iowa

Mahmoud El‐Khatib · University of Cincinnati

Prabir Roy‐Chaudhury · University of Cincinnati

Jeffrey H. Lawson · Duke University

Matthew T. Menard ·

Abstract

PRT-201 was not different from placebo for safety or efficacy measures. There was a suggestion for improved AVF primary patency with Low Dose PRT-201 that is now being studied in a larger clinical trial.

Topics & Keywords

Central Venous Catheters and Hemodialysis Vascular Procedures and Complications Cardiac and Coronary Surgery Techniques

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Vascular Access

Volume 14, Issue 2, pp. 143-151

DOI: 10.5301/jva.5000125

Field-Weighted Citation Impact: 7.89