Relationship between Initial Vancomycin Concentration‐Time Profile and Nephrotoxicity among Hospitalized Patients

2009545 citationsJournal Article

Authors

Thomas P. Lodise · Albany College of Pharmacy and Health Sciences

Nimish Patel · Albany College of Pharmacy and Health Sciences

Ben M. Lomaestro · Albany Medical Center Hospital

Keith A. Rodvold · American Association of Colleges of Pharmacy

Abstract

The results indicate that a vancomycin exposure-toxicity response relationship exists. The vancomycin trough value is the pharmacodynamic index that best describes this association.

Topics & Keywords

Antimicrobial Resistance in Staphylococcus Bacterial Identification and Susceptibility Testing Antibiotics Pharmacokinetics and Efficacy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

Volume 49, Issue 4, pp. 507-514

DOI: 10.1086/600884

Field-Weighted Citation Impact: 17.44