Identification of <i>PCDH1</i> as a Novel Susceptibility Gene for Bronchial Hyperresponsiveness

2009126 citationsJournal Articlegreen Open Access

Authors

Gerard H. Koppelman · Beatrix Kinderziekenhuis

Deborah A. Meyers · Wake Forest University

Timothy D. Howard · Wake Forest University

Shun Zheng · Wake Forest University

Greg Hawkins · Wake Forest University

Elizabeth J. Ampleford · Wake Forest University

Jianfeng Xu ·

Abstract

PCDH1 is a novel gene for BHR in adults and children. The identification of PCDH1 as a BHR susceptibility gene may suggest that a structural defect in the integrity of the airway epithelium, the first line of defense against inhaled substances, contributes to the development of BHR.

Topics & Keywords

Asthma and respiratory diseases Pediatric health and respiratory diseases Chronic Obstructive Pulmonary Disease (COPD) Research

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 180, Issue 10, pp. 929-935

DOI: 10.1164/rccm.200810-1621oc

Field-Weighted Citation Impact: 6.09

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Identification of <i>PCDH1</i> as a Novel Susceptibility Gene for Bronchial Hyperresponsiveness

Authors

Abstract

Topics & Keywords

Publication Details