Clinical and Molecular Studies of the Effect of Imatinib on Advanced Aggressive Fibromatosis (desmoid tumor)

2006315 citationsJournal Article

Authors

Michael C. Heinrich · Peter MacCallum Cancer Centre

Grant A. McArthur · Peter MacCallum Cancer Centre

George D. Demetri · Peter MacCallum Cancer Centre

Heikki Joensuu · Peter MacCallum Cancer Centre

Petri Bono · Peter MacCallum Cancer Centre

Richard Herrmann · Peter MacCallum Cancer Centre

Hal W. Hirte

Abstract

Imatinib is an active agent in the treatment of advanced AF. Imatinib response in AF patients may be mediated by inhibition of PDGFRB kinase activity.

Topics & Keywords

Soft tissue tumor case studies Sarcoma Diagnosis and Treatment Electromagnetic Simulation and Numerical Methods

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 24, Issue 7, pp. 1195-1203

DOI: 10.1200/jco.2005.04.0717

Field-Weighted Citation Impact: 19.59