Significance of defect severity in technetium-99m-MIBI SPECT at rest to assess myocardial viability: comparison with fluorine-18-FDG PET.

199498 citationsJournal Article

Authors

Carsten Altehoefer

Juergen vom Dahl · RWTH Aachen University

Marc Biedermann · RWTH Aachen University

R. Uebis · RWTH Aachen University

I. Beilin · RWTH Aachen University

Florence H. Sheehan · RWTH Aachen University

Peter Hanrath · RWTH Aachen University

Abstract

In patients with CAD, 99mTc-MIBI uptake underestimates myocardial viability in comparison to 18FDG-PET. Myocardial 99mTc-MIBI uptake therefore appears to reflect myocardial blood flow rather than myocardial viability. Patients with moderate and severe 99mTc-MIBI defects at rest may benefit from additional metabolic PET imaging prior to final therapeutic decisions.

Topics & Keywords

Radiopharmaceutical Chemistry and Applications Medical Imaging Techniques and Applications Cardiac Imaging and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PubMed

Volume 35, Issue 4, pp. 569-74

Field-Weighted Citation Impact: 7.77