Transtympanic Injections of N-acetylcysteine for the Prevention of Cisplatin-induced Ototoxicity

2011108 citationsJournal Article

Authors

Maria Riga · University Hospital of Alexandroupolis

Leonidas Chelis · Democritus University of Thrace

Stylianos Kakolyris · Democritus University of Thrace

Stergios Papadopoulos

Sofia Stathakidou

Eleni Chamalidou · University Hospital of Alexandroupolis

Nikolaos Xenidis · Democritus University of Thrace

Kyriakos Amarantidis

Abstract

Transtympanic injections of N-acetylcysteine seem to be a feasible and effective otoprotective strategy for the prevention of cisplatin-induced ototoxicity. Additional studies are required to further clarify the efficiency of this treatment and determine the optimal dosage and protocol.

Topics & Keywords

Hearing, Cochlea, Tinnitus, Genetics Vestibular and auditory disorders Ear and Head Tumors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Clinical Oncology

Volume 36, Issue 1, pp. 1-6

DOI: 10.1097/coc.0b013e31822e006d

Field-Weighted Citation Impact: 2.10