DNA methylation age of blood predicts all-cause mortality in later life

20151,342 citationsJournal Articlehybrid Open Access

Authors

Riccardo E. Marioni · University of Queensland

Sonia Shah · University of Queensland

Allan F. McRae · University of Queensland

Brian H. Chen · Framingham Heart Study

Elena Colicino · Harvard University

Sarah E. Harris · MRC Institute of Genetics and Molecular Medicine

Jude Gibson

Abstract

DNA methylation-derived measures of accelerated aging are heritable traits that predict mortality independently of health status, lifestyle factors, and known genetic factors.

Topics & Keywords

Epigenetics and DNA Methylation Intergenerational Family Dynamics and Caregiving Palliative Care and End-of-Life Issues

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Genome Biology

Volume 16, Issue 1, pp. 25-25

DOI: 10.1186/s13059-015-0584-6

Field-Weighted Citation Impact: 56.34