The TME Trial After a Median Follow-up of 6 Years

20071,187 citationsJournal Article

Authors

Koen Peeters · Leiden University Medical Center

Corrie A.M. Marijnen · The Netherlands Cancer Institute

Irıs D. Nagtegaal · Karolinska Institutet

Elma Meershoek‐Klein Kranenbarg

Hein Putter · Leiden University Medical Center

Theo Wiggers · University Medical Center Groningen

H.J.T. Rutten · Catharina Ziekenhuis

Abstract

With increasing follow-up, there is a persisting overall effect of preoperative short-term radiotherapy on local control in patients with clinically resectable rectal cancer. However, there is no effect on overall survival. Since survival is mainly determined by distant metastases, efforts should be directed towards preventing systemic disease.

Topics & Keywords

Colorectal Cancer Surgical Treatments Colorectal and Anal Carcinomas Colorectal Cancer Screening and Detection

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Surgery

Volume 246, Issue 5, pp. 693-701

DOI: 10.1097/01.sla.0000257358.56863.ce

Field-Weighted Citation Impact: 32.27