Long-term Cognitive and Psychological Outcomes in the Awakening and Breathing Controlled Trial

2010249 citationsJournal Articlegreen Open Access

Authors

James C. Jackson · Pulmonary and Allergy Associates

Timothy D. Girard · Geriatric Research Education and Clinical Center

Sharon M. Gordon · Geriatric Research Education and Clinical Center

Jennifer L. Thompson · Vanderbilt University

Ayumi Shintani · Vanderbilt University

Jason W. W. Thomason · Salem College

Brenda T. Pun

Abstract

In this trial, management of mechanically ventilated medical ICU patients with a wake up and breathe protocol resulted in similar cognitive, psychological, and functional outcomes among patients tested 3 and 12 months post-ICU. The proven benefits of this protocol, including improved 1-year survival, were not offset by adverse long-term outcomes. Clinical trial registered with www.clinicaltrials.gov (NCT 00097630).

Topics & Keywords

Intensive Care Unit Cognitive Disorders Anesthesia and Sedative Agents Family and Patient Care in Intensive Care Units

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 182, Issue 2, pp. 183-191

DOI: 10.1164/rccm.200903-0442oc

Field-Weighted Citation Impact: 14.49