Mycophenolate Mofetil or Intravenous Cyclophosphamide for Lupus Nephritis

20051,119 citationsJournal Articlebronze Open Access

Authors

Ellen M. Ginzler · State University of New York

Mary Anne Dooley · University of North Carolina at Chapel Hill

Cynthia Aranow · State University of New York

Mimi Kim

Jill P. Buyon · New York University Langone Orthopedic Hospital

Joan T. Merrill · Oklahoma Medical Research Foundation

Michelle Petri · Johns Hopkins University

Abstract

In this 24-week trial, mycophenolate mofetil was more effective than intravenous cyclophosphamide in inducing remission of lupus nephritis and had a more favorable safety profile.

Topics & Keywords

Systemic Lupus Erythematosus Research Liver Diseases and Immunity Inflammatory Bowel Disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 353, Issue 21, pp. 2219-2228

DOI: 10.1056/nejmoa043731

Field-Weighted Citation Impact: 42.52