A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

20026,504 citationsJournal Articlebronze Open Access

Authors

Marc J. van de Vijver · The Netherlands Cancer Institute

Yudong D. He

Laura van ‘t Veer · The Netherlands Cancer Institute

Hongyue Dai

Augustinus A. M. Hart · The Netherlands Cancer Institute

Dorien W. Voskuil · The Netherlands Cancer Institute

George J. Schreiber

Johannes L. Peterse · The Netherlands Cancer Institute

Abstract

The gene-expression profile we studied is a more powerful predictor of the outcome of disease in young patients with breast cancer than standard systems based on clinical and histologic criteria.

Topics & Keywords

Breast Cancer Treatment Studies Gene expression and cancer classification HER2/EGFR in Cancer Research

UN Sustainable Development Goals

No poverty

Publication Details

Published in: New England Journal of Medicine

Volume 347, Issue 25, pp. 1999-2009

DOI: 10.1056/nejmoa021967

Field-Weighted Citation Impact: 105.89