Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutation in Portuguese high-grade gliomas.

200867 citationsJournal Article

Authors

Marta Viana‐Pereira · University of Minho

José Manuel Lopes

Suzie Little

Fernanda Milanezi · Universidade do Porto

Diana Basto · University of Minho

Fernando Pardal · Hospital de São Marcos

Chris Jones

Rui Manuel Reis · Molecular Oncology (United States)

Abstract

We characterized, for the first time, EGFR molecular alterations in Portuguese patients with malignant glioma and identified a subpopulation of patients presenting putative biomarkers for EGFR-based therapies.

Topics & Keywords

Glioma Diagnosis and Treatment Lung Cancer Treatments and Mutations Cancer, Hypoxia, and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PubMed

Volume 28, Issue 2A, pp. 913-20

Field-Weighted Citation Impact: 1.59