Clinical trial: comparison of ibuprofen‐phosphatidylcholine and ibuprofen on the gastrointestinal safety and analgesic efficacy in osteoarthritic patients

200866 citationsJournal Articlebronze Open Access

Authors

Frank L. Lanza · Houston Institute for Clinical Research

Upendra Marathi · PLx Pharma (United States)

Bhupinderjit S. Anand · Baylor College of Medicine

Lenard M. Lichtenberger · The University of Texas Health Science Center at Houston

Abstract

Ibuprofen-PC is an effective osteoarthritic agent with an improved GI safety profile compared with ibuprofen in older OA patients, who are most susceptible to NSAID-induced gastroduodenal injury.

Topics & Keywords

Inflammatory mediators and NSAID effects Drug-Induced Adverse Reactions Antiplatelet Therapy and Cardiovascular Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Alimentary Pharmacology & Therapeutics

Volume 28, Issue 4, pp. 431-442

DOI: 10.1111/j.1365-2036.2008.03765.x

Field-Weighted Citation Impact: 3.93