Psychosis as a State of Aberrant Salience: A Framework Linking Biology, Phenomenology, and Pharmacology in Schizophrenia

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Authors

Shitij Kapur · Centre for Addiction and Mental Health

Abstract

The article provides a heuristic framework for linking the psychological and biological in psychosis. Predictions of this hypothesis, particularly regarding the possibility of synergy between psychological and pharmacological therapies, are presented. The author describes how the hypothesis is complementary to other ideas about psychosis and also discusses its limitations.

Topics & Keywords

Mental Health and Psychiatry Schizophrenia research and treatment Psychosomatic Disorders and Their Treatments

Publication Details

Published in: American Journal of Psychiatry

Volume 160, Issue 1, pp. 13-23

DOI: 10.1176/appi.ajp.160.1.13

Field-Weighted Citation Impact: 242.38

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Psychosis as a State of Aberrant Salience: A Framework Linking Biology, Phenomenology, and Pharmacology in Schizophrenia

Authors

Abstract

Topics & Keywords

Publication Details