Bioconductor: open software development for computational biology and bioinformatics

200412,479 citationsJournal Articlegold Open Access

Authors

Robert Gentleman · Dana-Farber/Harvard Cancer Center

Vincent J. Carey · Brigham and Women's Hospital

Douglas M. Bates · University of Wisconsin–Madison

Ben Bolstad · University of California, Berkeley

Marcel Dettling

Sandrine Dudoit · University of California, Berkeley

Byron Ellis · Harvard University

Abstract

The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. The goals of the project include: fostering collaborative development and widespread use of innovative software, reducing barriers to entry into interdisciplinary scientific research, and promoting the achievement of remote reproducibility of research results. We describe details of our aims and methods, identify current challenges, compare Bioconductor to other open bioinformatics projects, and provide working examples.

Topics & Keywords

Scientific Computing and Data Management Genetics, Bioinformatics, and Biomedical Research Single-cell and spatial transcriptomics

UN Sustainable Development Goals

Industry, innovation and infrastructure

Publication Details

Published in: Genome biology

Volume 5, Issue 10, pp. R80-R80

DOI: 10.1186/gb-2004-5-10-r80

Field-Weighted Citation Impact: 551.86