Association of Prostate Cancer Risk With Genetic Polymorphisms in Vitamin D Receptor and Androgen Receptor

1997591 citationsJournal Articlebronze Open Access

Authors

Sue A. Ingles · University of Southern California

R K Ross · University of Southern California

M C Yu · University of Southern California

R. W. Haile · University of Southern California

Ryan A. Irvine · University of Southern California

Giuseppe Pera · University of Southern California

Gerhard A. Coetzee

Abstract

These results are consistent with a multigenic model of prostate cancer susceptibility. On the basis of the joint effect of several genetic loci, one might ultimately be able to construct a risk profile to predict advanced disease, so that men whose disease is unlikely to progress to an advanced stage can possibly be spared aggressive treatment.

Topics & Keywords

Sexual Differentiation and Disorders Prostate Cancer Treatment and Research Hormonal and reproductive studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 89, Issue 2, pp. 166-170

DOI: 10.1093/jnci/89.2.166

Field-Weighted Citation Impact: 15.55