Recurrence due to Relapse or Reinfection With<i>Mycobacterium tuberculosis</i>: A Whole-Genome Sequencing Approach in a Large, Population-Based Cohort With a High HIV Infection Prevalence and Active Follow-up

2014178 citationsJournal Articlehybrid Open Access

Authors

José Afonso Guerra‐Assunção · London School of Hygiene & Tropical Medicine

Rein M G J Houben · London School of Hygiene & Tropical Medicine

Amelia C. Crampin · London School of Hygiene & Tropical Medicine

Themba Mzembe · Malawi Epidemiology and Intervention Research Unit

Kim Mallard · London School of Hygiene & Tropical Medicine

Francesc Coll · London School of Hygiene & Tropical Medicine

Abstract

While some of the factors determining recurrence depend on the patient and their treatment, differences in the Mycobacterium tuberculosis genome appear to have a role in both relapse and reinfection.

Topics & Keywords

Tuberculosis Research and Epidemiology Mycobacterium research and diagnosis Pneumocystis jirovecii pneumonia detection and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Infectious Diseases

Volume 211, Issue 7, pp. 1154-1163

DOI: 10.1093/infdis/jiu574

Field-Weighted Citation Impact: 7.01