CD8+ T-Cell Content in Diagnostic Lymph Nodes Measured by Flow Cytometry Is a Predictor of Survival in Follicular Lymphoma

2007146 citationsJournal Article

Authors

Björn E. Wahlin · Integrated Cardio Metabolic Centre

Birger Christensson · Karolinska Institutet

Eva Kimby · Integrated Cardio Metabolic Centre

Abstract

Higher levels of CD8+ T cells predict a better prognosis, and these data support an important role for nonmalignant immune cells in the biology of follicular lymphoma. Evaluating the CD8+ T cells by flow cytometry at diagnosis may provide prognostic information.

Topics & Keywords

Lymphoma Diagnosis and Treatment Immune Cell Function and Interaction Cutaneous lymphoproliferative disorders research

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: Clinical Cancer Research

Volume 13, Issue 2, pp. 388-397

DOI: 10.1158/1078-0432.ccr-06-1734

Field-Weighted Citation Impact: 7.64