Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

2013393 citationsJournal Articlehybrid Open Access

Authors

Eileen M. Moore · University of Melbourne

Alastair Mander · Barwon Health

David Ames · National Ageing Research Institute

Mark A. Kotowicz · University of Melbourne

Ross Carne · Deakin University

Henry Brodaty · UNSW Sydney

Mark Woodward ·

Abstract

Metformin use was associated with impaired cognitive performance. Vitamin B12 and calcium supplements may alleviate metformin-induced vitamin B12 deficiency and were associated with better cognitive outcomes. Prospective trials are warranted to assess the beneficial effects of vitamin B12 and calcium use on cognition in older people with diabetes who are taking metformin.

Topics & Keywords

Folate and B Vitamins Research Metabolism, Diabetes, and Cancer Diabetes Treatment and Management

Publication Details

Published in: Diabetes Care

Volume 36, Issue 10, pp. 2981-2987

DOI: 10.2337/dc13-0229

Field-Weighted Citation Impact: 21.20

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Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

Authors

Abstract

Topics & Keywords

Publication Details