Probable medication-overuse headache: The effect of a 2-month drug-free period

I read the article by Zeeberg et al.1 with interest in which they emphasize the therapeutic importance of weaning patients suspected of having medication overuse headache (MOH). Do the authors believe there is a possibility that the observed improvement in headache could be partially due to an “inverse” placebo effect? The placebo effect can be defined as “improvement in the condition of a patient that occurs in response to treatment but cannot …