Progressive Orf Virus Infection in a Patient with Lymphoma: Successful Treatment Using Imiquimod

200776 citationsJournal Articlebronze Open Access

Authors

Edith Lederman · National Center for Infectious Diseases

Gareth M. Green · Kaiser Permanente Santa Rosa Medical Center

H. E. DeGroot

Patrick Dahl · Kaiser Permanente Santa Rosa Medical Center

Erinn Hoag Goldman · Centers for Disease Control and Prevention

Patricia W. Greer · Centers for Disease Control and Prevention

Yu Li · Centers for Disease Control and Prevention

Abstract

Orf virus is a parapoxvirus that infects small ruminants worldwide. We present the case report of a 73-year-old woman with non-Hodgkins lymphoma who developed progressive orf virus lesions that were unresponsive to surgical debridement and to cidofovir therapy. The patient's orf virus infection was successfully treated with topical imiquimod despite progression of her malignancy.

Topics & Keywords

Poxvirus research and outbreaks Virus-based gene therapy research Herpesvirus Infections and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

Volume 44, Issue 11, pp. e100-e103

DOI: 10.1086/517509

Field-Weighted Citation Impact: 1.02