Inactivation of viruses in platelet concentrates by photochemical treatment with amotosalen and long‐wavelength ultraviolet light

2005171 citationsJournal Articlebronze Open Access

Authors

Lily Lin · University of California, San Francisco

Carl V. Hanson · University of California, San Francisco

Harvey J. Alter · California Health and Human Services Agency

Valérie Jauvin · University of California, San Francisco

Kristen A. Bernard · Institute for Transfusion Medicine

Krishna K. Murthy · Cerus (United States)

Peyton Metzel

Abstract

PCT inactivates a broad spectrum of pathogenic, blood-borne viruses. Inactivation of viruses in PLT concentrates with amotosalen and UVA offers the potential to prospectively prevent the majority of PLT transfusion-associated viral diseases.

Topics & Keywords

Virus-based gene therapy research Hematopoietic Stem Cell Transplantation Hepatitis B Virus Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Transfusion

Volume 45, Issue 4, pp. 580-590

DOI: 10.1111/j.0041-1132.2005.04316.x

Field-Weighted Citation Impact: 5.97